Welcome to Dicerna

Dicerna Pharmaceuticals is a private, venture-backed biopharmaceutical company developing novel therapeutic agents in multiple therapeutic areas based on its proprietary Dicer Substrate Technology™, which triggers RNA interference (RNAi) in a potent and specific manner.

The technology upon which Dicerna is based was discovered by Dicerna co-founders John Rossi, Ph.D., a Professor in the Division of Molecular Biology and Dean, Graduate School of Biological Sciences at City of Hope's Beckman Research Institute in Duarte, California, and Mark Behlke, M.D., Ph.D., at Integrated DNA Technologies in Coralville, Iowa.

Dicerna has raised a total of $21.4 million in venture capital led by Oxford Bioscience Partners, Skyline Ventures and Abingworth. Dicerna is led by seasoned biotechnology industry veterans including James C. Jenson, Ph.D., CEO, Roberto Guerciolini, M.D., SVP Pharmaceutical Development, Bob D. Brown, Ph.D., SVP Research, and Martin Williams, SVP and Chief Business Officer.

SCIENCE & TECHNOLOGY

Dicerna's approach offers strong advantages over conventional RNAi.

Using its Dicer Substrate Technology™, Dicerna offers a route to greater potency via the natural processing pathway for small interfering RNAs.

See the Dicerna difference

THE DICERNA TEAM

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The Dicerna team is comprised of leaders in the fields of RNAi and oligonucleotide therapeutics. The company is based in Boston. »